生物通报道:来自厦门大学生命科学学院细胞生物学与肿瘤细胞工程教育部重点实验室(Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering),清华大学生命科学与生物技术系教育部蛋白质科学重点实验室,香港理工大学生物化学系的研究人员在之前证明了Axin是一种可以激活JNK MAP激酶的骨架蛋白,并独家阐明了整个信号通路的分子与生化机理的基础上,进一步识别出了一种由Axin/JNK信号发挥作用,由Aida抑制的脊椎动物胚胎发生的背外侧途径。这一研究成果公布在《Developmental Cell》杂志上。
Developmental Cell, Vol 13, 268-282, 07 August 2007 A β-Catenin-Independent Dorsalization Pathway Activated by Axin/JNK Signaling and Antagonized by Aida [Abstract]
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